A comparison involving 420 people found different gut microbial profiles in depression accompanied by REM sleep behavior disorder than in depression alone. The combined group’s profile more closely resembled that of people…
Read story: Gut profiles differ when depression accompanies a specific sleep disorder ↗An analysis of 38,283 women compared dietary patterns with weight change across the years before and after menopause. Patterns expected to produce…
Read story: Weight change around menopause: a study of whole dietary patterns ↗In 1,350 CARDIA participants averaging age 61, blood biomarkers were measured at year 35. Some Alzheimer-related patterns were associated with poorer concurrent…
Read story: Blood markers linked to cognitive changes in midlife ↗Thirty-seven older adults completed twelve weeks of supervised exercise twice weekly, emphasizing muscle loading while lengthening. Stair climbing and timed rising-and-walking performance…
Read story: Older-adult exercise study finds mixed changes in physical function ↗Researchers examined eight familial melanoma genes in nearly 697,000 people across two datasets. Disease-associated variants exceeded a 2.5% prevalence threshold among people…
Read story: Genetic risk in melanoma: what age at diagnosis and multiple tumours reveal ↗In the RECOVER-VITAL analysis of 959 adults, researchers evaluated fifteen or twenty-five days of nirmatrelvir–ritonavir. At day ninety, neither regimen significantly improved…
Read story: Extended antiviral treatment showed no benefit in long COVID trial ↗The SenCat project compared more than 30 senescence conditions across 14 human cell types. RNA and protein measurements revealed no single marker…
Read story: No single signature identifies every senescent cell ↗In newborn mice, C. difficile colonization changed intestinal inflammatory and repair responses without obvious illness. Some cellular changes persisted into adulthood. Tissue…
Read story: A symptom-free gut bacterium may leave lasting developmental changes ↗Fifteen people with peanut allergy received capsules containing gut microbes from non-allergic donors. After four months, tolerated peanut amounts increased in three…
Read story: Could gut microbes help with peanut allergy? An early small study ↗After quality control, researchers compared hippocampal tissue from 11 donors with a history of depression and 19 without. Depression was associated with…
Read story: Does nerve-cell development differ in depression? Clues from brain tissue ↗In experiments starting with 20-month-old female mice, semaglutide improved some movement and cognitive measures. With treatment continued until death, median lifespan was…
Read story: Semaglutide extended lifespan in older female mice: what does it mean for people? ↗Laboratory and animal models showed that abnormal tau changes could trigger reverse electron flow in mitochondria, which could further alter tau. An…
Read story: A new connection between tau protein and cellular energy production ↗Implanted electrodes translated brain signals into an avatar’s speech and upper-body movements. Three people with severe speech paralysis participated; simultaneous speech and…
Read story: Brain signals combine speech and gestures in a digital avatar ↗Researchers followed 296 older adults who were cognitively normal at baseline. Among those with Alzheimer-related brain changes, more daily steps were associated…
Read story: Walking and brain health: benefits may not require 10,000 steps ↗Laboratory tests examined 39 sweeteners and 25 gut bacterial strains. Their effects could change in the presence of caffeine and certain medicines.
Read story: Sweeteners and gut bacteria may have a more complex relationship ↗Researchers studied two-way communication between brain circuits controlling sleep and growth hormone in mice.
Read story: The sleeping body stays busy: a sleep–hormone link in mice ↗A hydrocortisone-versus-placebo experiment analysed 26 participants to explore brain networks involved in emotional memory.
Read story: Why do some memories feel more vivid? ↗Data from 22,851 US participants collected during 2001–2018 suggested that inadequate iodine intake became more common.
Read story: Are people getting enough iodine? US data point to a growing gap ↗
